Trans-1,2-diaminocyclohexane
CAS 1121-22-8
HS 2942000000
Product name: Trans-1,2-diaminocyclohexane CAS No.: 1121-22-8 Molecular formula: C6H14N2 Applications: Core Industrial Applications 1. Third-generation platinum anticancer drug oxaliplatin dedicated core intermediate (largest essential demand) Full synthesis chain: (R,R)-trans-1,2-cyclohexanediamine → dichloroplatinum complex → oxalate displacement → oxaliplatin API. Oxaliplatin for colorectal and ovarian cancer — only (R,R) chiral scaffold has anticancer activity; irreplaceable feedstock. 2. Asymmetric catalysis chiral ligands 1. C2-symmetric Schiff bases and phosphinamide chiral ligands for Suzuki, hydrogenation and epoxidation asymmetric catalysis; 2. Metal-catalyzed extraction and chiral chromatography stationary-phase resolving agents. 3. High-end epoxy resin curing agents Cyclic diamine thermal stability far superior to aliphatic chain diamines; cured films resist acid/alkali with low yellowing — anti-corrosion flooring, electronic potting, metal primers. 4. Other fine chemicals 1. Lubricant and pipeline acid-pickling corrosion inhibitors adsorbing on metal to form protective film; 2. Specialty surfactants and polyamide resin modification monomers; 3. Peptide synthesis and heterocyclic drug chiral scaffolds.
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