(1R,4R)-4-aminocyclohexanol

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CAS 27489-62-9

Product name: (1R,4R)-4-aminocyclohexanol
CAS No.: 27489-62-9
Molecular formula: C6H13NO
Applications:
III. Core Industrial Applications (most core: ambroxol hydrochloride API intermediate)
1. Pharmaceutical field (largest global consumption)
1. Ambroxol hydrochloride (Mucosolvan) dedicated intermediate — core expectorant feedstock; reductive amination condensation with 2-amino-3,5-dibromobenzaldehyde directly synthesizes ambroxol product — key chiral scaffold for entire process; trans configuration determines drug efficacy and purity.
2. Other drug synthesis: fenfluramine sedative, chlorpheniramine antihistamine, pyrimethamine antimalarial intermediates; CNS and anti-inflammatory chiral synthesis building blocks.
2. Agrochemical fine chemicals
• Insecticides (fenvalerate, valerate), triazole fungicides and herbicide synthesis feedstock;
• Aminocyclohexyl ester and heterocyclic pesticide intermediate preparation.
3. Polymers & surfactants
Polyamide and polyester modification monomers; amphoteric surfactant and emulsifier feedstock; chiral chromatography resolving reagent.
4. General organic synthesis building block
Schiff bases, coordination ligands and ester derivative synthesis; enzymatic esterification reaction substrate.
VI. Storage & Handling
1. Cool dry sealed warehouse protec

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