(1R,2R)-(-)-1,2- diaminocyclohexane acid

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CAS 20439-47-8

HS 2921300090

Product name: (1R,2R)-(-)-1,2- diaminocyclohexane acid
CAS No.: 20439-47-8
Molecular formula: C6H14N2
Applications:
Core Applications
1. Oxaliplatin API exclusive chiral intermediate (core application)
Synthesis route: (R,R)-trans-1,2-cyclohexanediamine → dichloro(1R,2R-cyclohexanediamine)platinum → oxalate displacement → oxaliplatin API. Oxaliplatin for colorectal, gastric and ovarian cancer chemotherapy — only levorotatory (R,R) configuration has antitumor activity; dextrorotatory and racemic forms are inactive — irreplaceable dedicated feedstock.
2. Asymmetric synthesis chiral building block
1. Chiral Salen ligand preparation for alkene epoxidation and asymmetric ketone hydrogenation catalysis;
2. Chiral resolving agent for organic acids and alcohols;
3. Pharmaceutical and agrochemical chiral intermediate scaffold.
3. Specialty epoxy curing agent
High weatherability, low-yellowing anti-corrosion flooring, electronic potting compounds and marine anti-corrosion coatings — cyclic structure improves film acid/alkali and thermal stability.

Supplied by Shanghai Blue Aurora Fine Chemical Technology Co., Ltd. — flexible MOQ, mixed shipments, worldwide delivery.