1,1-cyclobutanedicarboxylic

Name: Shanghai Blue Aurora Fine Chemical Technology Co., Ltd.
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CAS 5445-51-2

HS 2917209090

Product name: 1,1-cyclobutanedicarboxylic
CAS No.: 5445-51-2
Molecular formula: C6H6O4
Applications:
Core Industrial Applications (~95% global use in platinum anticancer drugs)
1. Second-generation chemotherapy carboplatin dedicated core ligand (largest use)
Full synthesis chain: 1,1-cyclobutanedicarboxylic acid → disodium salt → reaction with cis-diammineplatinum → carboplatin API. Key leaving ligand in carboplatin molecule — vs cisplatin, greatly reduces nephrotoxicity; clinical use in ovarian, lung and head/neck tumors — essential irreplaceable intermediate.
2. Other platinum antitumor drug intermediates
Feedstock for nedaplatin, enloplatin, dicycloplatin and novel platinum chemotherapies; also carboplatin pharmacopoeial impurity reference material feedstock.
3. Fine organic synthesis extensions
1. Dibasic acid monomer for specialty polyesters and polyamides;
2. Metal coordination ligand for catalysis and fluorescent materials;
3. Dye and coating modification aid improving resin adhesion and weatherability.

Supplied by Shanghai Blue Aurora Fine Chemical Technology Co., Ltd. — flexible MOQ, mixed shipments, worldwide delivery.