4-(Trifluoromethoxy)aniline

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CAS 461-82-5

HS 2922299090

Product name: 4-(Trifluoromethoxy)aniline
CAS No.: 461-82-5
Molecular formula: C7H6F3NO
Applications:
Core Industrial Applications
1. Agrochemical intermediate (largest demand): core feedstock for benzoylurea insecticides lufenuron, flufenoxuron and metaflumizone; herbicides and insect growth regulator building blocks; −OCF3 greatly improves insecticidal activity, reduces crop residues and improves rainfastness
2. Pharmaceutical intermediate: amyotrophic lateral sclerosis and neuroprotective drugs (riluzole impurity reference); antitumor and anti-inflammatory targeted drug building blocks; diazotization and coupling to fluorinated heterocyclic and biphenyl APIs; trifluoromethoxy extends in vivo half-life and reduces hepatic/renal metabolic clearance
3. Organic dyes/photoelectric materials: disperse dyes and fluorinated functional dye diazotization feedstock; OLED and liquid-crystal intermediates adjusting molecular polarity and optimizing dielectric and emission performance
4. General organic synthesis building block: 4-bromotrifluoromethoxybenzene, 4-cyanotrifluoromethoxybenzene, 4-hydroxytrifluoromethoxybenzene and downstream fine fluorides

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