2-Fluorobenzotrifluoride
CAS 392-85-8
HS 2903999090
Product name: 2-Fluorobenzotrifluoride CAS No.: 392-85-8 Molecular formula: C7H4F4 Applications: Core Industrial Applications 1. Pharmaceutical intermediate: CNS, anti-inflammatory and antitumor targeted drug dedicated building block; unique ortho dual-fluoro spatial structure optimizes drug–target binding; −CF3 improves metabolic stability, extends half-life and reduces hepatic/renal clearance; nitration, reduction and nucleophilic substitution to o-fluorotrifluoromethylaniline, phenol and ether APIs 2. Agrochemical intermediate: novel low-toxicity fungicides and insect growth regulators; dual fluorine substitution improves foliar adhesion, rainfastness and low crop residues for fluorinated heterocyclic pesticides 3. Organocatalysis ligands (specialty demand): ring modification with phosphine and nitrogen heteroatoms for asymmetric catalysis chiral fluorinated ligands; ortho F and trifluoromethyl synergistically control sterics and electronics to greatly improve enantioselectivity 4. Liquid crystal and photoelectric materials: premium liquid-crystal monomers and OLED functional-layer intermediates; tetrafluoro structure precisely adjusts dielectric constant, lowers liquid-crystal viscosity and improves screen response; weather-resistant fluorinated disperse dyes 5. General or
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