Chloroacetyl chloride

Name: Shanghai Blue Aurora Fine Chemical Technology Co., Ltd.
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CAS 79-04-9

HS 2915900090

Product name: Chloroacetyl chloride
CAS No.: 79-04-9
Applications:
Core Industrial Applications
1. Pharmaceutical intermediates (fine chemical essential demand)
• CNS, antifungal and anthelmintic synthesis: chloroacetyl side-chain introduction for praziquantel, fluconazole, diazepam, lidocaine and pirenzepine
• Key acylation feedstock for β-lactam antibiotics, H2-receptor antagonists and antiemetic azasetron
• Amino protection/modification reagent for peptide synthesis and chiral intermediates; provides −COCH2Cl active linker arm; subsequent cyclization with methylamine or thiol compounds
2. Agrochemical intermediates (largest consumption field)
• Amide herbicides: core feedstock for alachlor, acetochlor, butachlor and metolachlor; acylation with substituted anilines gives herbicide precursors
• Triazine herbicides (atrazine, prometryn), organophosphorus insecticides (dimethoate, omethoate) and fungicide imazalil dedicated acylation agent
3. Other fine chemicals
• Dye and fragrance acylation modification enhancing color fastness and aroma stability
• Ion-exchange resin and water-treatment chelating resin functionalization feedstock; introduces chloromethyl active sites
• GC derivatization reagent for quantitative derivatization of trace amines

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