2-chloroisobutyryl chloride

CAS 13222-26-9

HS 2915900090

Product name: 2-chloroisobutyryl chloride
CAS No.: 13222-26-9
Molecular formula: C4H6Cl2O
Applications:
Core Industrial Applications
1. UV photoinitiator core feedstock (largest use)
Synthesis of commercial α-hydroxy ketone photoinitiators PI-906 and PI-907 for UV coatings, inks, 3D-printing resins and photoresists; dual chlorine functional groups are characteristic photoinitiator molecule backbone.
2. Controlled polymerization (ATRP initiator intermediate)
Tertiary chlorine + acyl chloride difunctional structure for preparing atom transfer radical polymerization initiators; precisely controls polyacrylic, epoxy resin molecular weight for waterborne coatings, functional polymers and block copolymer synthesis.
3. Pharmaceutical fine intermediates
• Sterically hindered amide drug synthesis: selective acylation reagent for anti-inflammatory, CNS inhibitor and chiral small-molecule APIs; gem-dimethyl steric hindrance reduces side reactions and improves chiral intermediate purity
• Peptide amino protection reagent; constructs drug side chains containing tertiary carbon branches
4. Agrochemical and dye intermediates
• Herbicide and fungicide branch modification enhancing molecular hydrolysis stability
• Premium solvent dye and fluorescent dye acylation modification enhancing lightfastness

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